ER Stress, Autophagy & Immune System

26-27 January 2017, Bruges, Belgium
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ER Stress, Autophagy & Immune System

ER stress and autophagy are evolutionary conserved cellular pathways that play important roles in our defense against proteotoxic stress and infections.  They are likely to be major pathways in the pathogenesis of multiple inflammatory and immunological diseases, and could be exploited for new therapeutic interventions. The goal of this conference on ‘ER stress, autophagy & immune system’, is to bring together world leaders in this field of research and have them present their latest advances and discoveries. Junior researchers are encouraged to submit an abstract of their research as a number of abstracts will be selected to give a short talk during one of the plenary sessions.

In addition to a great scientific program, there will be many opportunities to interact with the speakers and participants during the breaks, poster sessions and conference dinner. 

The meeting is held in the Old St.-John’s Hospital, one of the oldest hospitals in Europe, in the center of picturesque Bruges.

Meet the Expert session with: Dr. Beth Levine - HHMI & Texas Southwestern Medical Center, US

We offer all junior researchers the opportunity to join our ‘Meet the Expert' session with Dr. Beth Levine. During an informal round table discussion on the 27th of January, PhD students and postdocs will have the exclusive opportunity to ask any question/advise related to their research and careers. If you are interested in joining the session, then send an e-mail to conferences@vib.be. Seating is limited.

Top speakers: 

Herbert ‘Skip’ Virgin

Washington University - School of Medicine, US

Michael Karin

University of California - Department of Pharmacology, US

Beth Levine

HHMI & Texas Southwestern Medical Center, US

Hidde Ploegh

Whitehead Institute for Biomedical Research, US

David Ron

Cambridge Institute for Medical Research, UK

Richard Blumberg

Harvard Medical School, US

Julie Magarian Blander

Weill Cornell Medicine, US

Adrian Liston

VIB Translational Immunology Lab, KU Leuven, BE

Renée M. Tsolis

Davis School of Medicine - University of California, Davis, US

Anne Bertolotti

University of Cambridge, UK

Kodi Ravichandran

VIB Inflammation Research Center, UGent, BE

Vojo Deretic

University of New Mexico, US

Ineke Braakman

University of Utrecht, NL

Sébastien Gaumer

Université de Versailles Saint-Quentin-en-Yvelines, FR

Christian Münz

University of Zurich, CH

Sophie Janssens

VIB-UGent Center for Inflammation Research, BE

Miguel A Sanjuan

MedImmune, US

Patrizia Agostinis

Department of Cellular and Molecular Medicine, KU Leuven, BE
Download the program: 

Thursday, 26 January, 2017

Thursday, 26 January, 2017
08:45 - 09:10
Registration & Welcome Coffee
09:10 - 09:15
Welcome
09:15 - 12:45
Session 1: Protein folding homeostasis
09:15 - 10:15
KEYNOTE: Protein folding homeostasis in the ER
David Ron
Cambridge Institute for Medical Research, UK
Academic speaker
10:15 - 10:50
Strategies to survive protein quality control failure and prevent neurodegenerative diseases
Anne Bertolotti
University of Cambridge, UK
Academic speaker
10:50 - 11:20
Coffee Break
11:20 - 11:55
Protein folding and stress in the ER
Ineke Braakman
University of Utrecht, NL
Academic speaker
11:55 - 12:30
Regulation of ER quality control
Hidde Ploegh
Whitehead Institute for Biomedical Research, US
Academic speaker
12:30 - 12:45
Selected abstract: Viral control of autophagy to reprogram the host cell secretome
Jennifer Corcoran
Dalhousie University, CA
Academic speaker
12:45 - 12:50
Sponsored Talk: Amnis capabilities for Immunological research
Erwin Swart
Cellular Analysis Specialist at Merck Millipore, NL
Company speaker
12:50 - 13:30
Lunch
13:30 - 14:15
Poster Session - odd numbers
14:15 - 17:55
Session 2: The UPR in inflammatory diseases
14:15 - 14:50
Mitochondrial Control of Inflammation
Michael Karin
University of California - Department of Pharmacology, US
Academic speaker
14:50 - 15:25
Fruitfly as a tool to uncover the mechanisms of ER stress response in human disease models
Sébastien Gaumer
Université de Versailles Saint-Quentin-en-Yvelines, FR
Academic speaker
15:25 - 15:40
Selected abstract: Activation of UPR transducer ATF6α and increases in PDIA3 is required for influenza A virus (IAV) propagation and development of lung immunopathology
Vikas Anathy
University of Vermont, US
Academic speaker
15:40 - 16:10
Coffee Break
16:10 - 16:45
The role of the IRE1alpha/XBP1-branch in dendritic cells
Sophie Janssens
VIB-UGent Center for Inflammation Research, BE
Academic speaker
16:45 - 17:20
Endoplasmic reticulum stress for immunotherapy against cancer; from translational medicine to molecular mediators
Patrizia Agostinis
Department of Cellular and Molecular Medicine, KU Leuven, BE
Academic speaker
17:20 - 17:55
Immune Mechanisms of Intestinal Injury Derived from ER stress in the Intestinal Epithelium
Richard Blumberg
Harvard Medical School, US
Academic speaker
18:00 - 19:00
Reception
19:30 - 22:30
Conference Dinner

The Organizing Committee consists of:

Bart Lambrecht, VIB Center for Inflammation Research, UGent
Hamida Hammad, VIB Center for Inflammation Research, UGent
Sophie Janssens, VIB Center for Inflammation Research, UGent
Geert Van Loo, VIB Center for Inflammation Research, UGent
Adrian Liston, VIB-KU Leuven Center for Brain & Disease Research, KU Leuven
Mark Veugelers, VIB Science Policy Manager
Evy vierstraete, VIB Manager Science Events

Friday, 27 January, 2017

Friday, 27 January, 2017
08:45 - 09:15
Welcome Coffee
09:15 - 12:45
Session 3: Autophagy in physiology and pathology
09:15 - 10:15
KEYNOTE: Mitophagy and Links to Immunity
Beth Levine
HHMI & Texas Southwestern Medical Center, US
Academic speaker
10:15 - 10:50
The key intersections of autophagy and immunity
Vojo Deretic
University of New Mexico, US
Academic speaker
10:50 - 11:20
Coffee Break
11:20 - 11:55
LC3-associated phagocytosis in autoimmunity
Miguel A Sanjuan
MedImmune, US
Academic speaker
11:55 - 12:30
Title to be announced
Kodi Ravichandran
VIB Inflammation Research Center, UGent, BE
Academic speaker
12:30 - 12:45
Selected abstract: The ubiquitin-ligase Smurf1 functions in selective autophagy of M. tuberculosis and anti-tuberculous host defense
Michael Shiloh
University of Texas Southwestern Medical Center, US
Academic speaker
12:45 - 12:50
Sponsored talk: Tools & techniques to study autophagy using fluorescence microscopy
Nick Dolman
Senior Staff Scientist at ThermoFisher, US
12:50 - 13:30
Lunch
13:30 - 14:15
Poster Session - even numbers
14:15 - 17:55
Session 4: Host defense, ER stress and autophagy
14:15 - 14:50
Stress-induced ER-phagy and the type-1 interferon response
Julie Magarian Blander
Weill Cornell Medicine, US
Academic speaker
14:50 - 15:25
Innate immune sensing of ER stress via NOD1/NOD2
Renée M. Tsolis
Davis School of Medicine - University of California, Davis, US
Academic speaker
15:25 - 15:40
Selected abstract: The p110δ PI3K isoform is a signalling component of NOD2-mediated gastrointestinal immunity and inflammation
Esra Aksoy
Barts and the London School of Medicine and Dentistry, Queen Mary University, US
Academic speaker
15:40 - 16:10
Coffee Break
16:10 - 16:45
ER stress in diabetes: Beta cell fragility
Adrian Liston
VIB Translational Immunology Lab, KU Leuven, BE
Academic speaker
16:45 - 17:20
Autophagy genes in inflammation and immunity
Herbert ‘Skip’ Virgin
Washington University - School of Medicine, US
Academic speaker
17:20 - 17:55
Non-canonical roles of autophagy proteins in endocytosis and exocytosis during infection
Christian Münz
University of Zurich, CH
Academic speaker
17:55 - 18:10
Closing Remarks

The Organizing Committee consists of:

Bart Lambrecht, VIB Center for Inflammation Research, UGent
Hamida Hammad, VIB Center for Inflammation Research, UGent
Sophie Janssens, VIB Center for Inflammation Research, UGent
Geert Van Loo, VIB Center for Inflammation Research, UGent
Adrian Liston, VIB-KU Leuven Center for Brain & Disease Research, KU Leuven
Mark Veugelers, VIB Science Policy Manager
Evy vierstraete, VIB Manager Science Events

Hashtag: 
#ERStress17