Applications and Business Development Scientist, Diagenode Inc., US

BIO

Sharon Squazzo is an Applications and Business Development Scientist at Diagenode, Inc. Her responsibilities in this role encompass the technical development of Diagenode’s epigenomic product portfolio. Prior to joining Diagenode in 2010, Sharon was a Senior Research Associate in Dr. Peggy Farnham’s lab at the UC Davis Genome Center where she identified and characterized the mammalian gene targets of the transcriptional silencing complex PRC2 in embryonal and cancer cells using various epigenomic methods. Sharon received a B.S. degree in microbiology from the University of Massachusetts Amherst and has been working in the field of gene transcription and chromatin research for the past twenty years.


PUBLICATIONS

Komashko el al., Using ChIP-chip technology to reveal common principles of transcriptional repression in normal and cancer cells. Genome Res. 2008 Apr;18(4):521-32

Rinn et al., Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 2007 Jun 29;129(7):1311-23

ENCODE Consortium, Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project., Nature. 2007 Jun 14;447(7146):799-816

O’Geen et al., Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. PloS Genet. 2007 Jun;3(6):e89

Squazzo et al., Suz12 binds to silenced regions of the genome in a cell-type specific manner. Genome Res. 2006 Jul;16(7):890-900


MORE INFO

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