International Meeting on Optical Biosensors
In memory of Roger Y. Tsien on the 10th year anniversary of his Nobel prize
Add to calendarOrganized by CNRS, ImaBio and IRC
Biological processes show extreme complexity orchestrated both in space and time. To face this complexity, it has been necessary, as pointed out by R.Y. Tsien in his lecture "Unlocking Cell Secrets with Light Beams and Molecular Spies" (Heineken Prize for Biochemistry and Biophysics, 2002), to develop fluorescent spies in order to analyze, quantify in real time and decrypt very sophisticated cellular mechanisms. The recent explosion of fluorescent biosensors development opens a new field of investigation by allowing the analysis of extremely specific biological events at the level of cellular organelles, individual cells, tissues and even entire living organisms in physiological and pathological conditions. The development and the use of these tools require solving a number of conceptual, experimental and technological problems concerning both the biosensors themselves and the tools to follow them. Equally important, a range of new developments including optogenetic and optochemical tools allow systematic perturbation of biochemical processes while they are read out by optical biosensors.
The purpose of this conference is to gather and consolidate the expertise in the field of biosensors and to promote the reflection and the exchange of information so as to accelerate the development of these new dynamic imaging approaches in all areas of biology and biomedical sciences.
Poster information:
Format: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation
Confirmed speakers
Program
Day 1 - Thursday, 15 November, 2018
The discovery of GFP and a tribute to the contributions of R.Y. Tsien
Robert Campbell
Chairs: Dr. Oliver Griesbeck and Dr. Fabienne Mérola
This session will feature the novel fluorescent proteins and their specific applications in biosensor imaging.
Theodorus Gadella
Marie Erard
Antoine Royant
Shigekazu Oda
Tou Cheu Xiong: Iron live imaging in Arabidopsis thaliana,
Giulia Bertolin: Optimization of fluorophores and analysis approaches to ameliorate a FRET biosensor of the mitotic kinase AURKA,
Oleg Dyachok: Zn2+-SIGNALING IN INSULIN-SECRETING BETA-CELLS,
Timothy Dore: Photoactivatable dopamine to explore the function of dopaminergic neurons and circuits.
Peter Dedecker
Joachim Goedhart
Erik Rodriguez
Chairs: Dr. May Morris and Dr. Alessandro Esposito
In this session we will hear about high-content screening applications and discuss the newest developments aimed at marrying FRET- and FLIM imaging in this context.
Kees Jalink
May Morris
Matteo Guerra
Dennis Botman
Day 2 - Friday, 16 November, 2018
Jin Zhang
Chairs: Dr. Clotilde Randriamampita and Dr. Pierre Vincent
Imaging biosensors in a physiologically-relevant preparation can be challenging. This session will present a selection of biological discoveries in which biosensor imaging was instrumental.
Anders Tengholm
Franck Riquet
John Albeck
Isabelle Limon
Pierre Vincent
Julie Perroy
Michael Russwurm
Chairs: Pr. Franck Riquet and Pr. Juan Llopis
Better biosensors allow for more applications. This session will focus on how biosensor performances can be improved, in terms of signal, photostability, vectorization etc...
Oliver Griesbeck
Kazuhiro Aoki
R Harkes: A gated solid-state camera for high throughput frequency domain FLIM measurements of cAMP dynamics,
Ana Clara Fernandes (Nikon): Bring high resolution, high content imaging to life,
Fabien Miart: Functional in vivo imaging of pH and Ca2+ dynamics in Arabidopsis thaliana growing seedlings using biosensors and the VIP-box,
Jochen Sieber (Leica): SP8 FALCON – a new approach for lifetime imaging.
Carsten Schultz
Sergi Padilla-Parra
Chiwei Man
Rym Cherif
'Fiers-Schell-Van Montagu' building
Day 3 - Saturday, 17 November, 2018
Wolf Frommer
Chairs: Dr. Saskia Lippens and Pr. Peter Dedecker
The pros and cons of the various detection instruments will be illustrated and discussed, as well as how the signal can be quantified and deemed relevant of a biological event.
Marc Tramier
Alessandro Esposito
Andre Zeug
Alain Henri Lombard
Jussep Salgado
Ewa Sieliwonczyk
Bas Ponsioen
Sean Warren
Organizing committee
Saskia Lippens
Juan Llopis
May Morris
Clotilde Randriamampita
Franck Riquet
Peter Vandenabeele
Pierre Vincent
Kees Jalink
Peter Dedecker
Oliver Griesbeck
Abstracts
This list will only be available for registered attendees of the event.
Attendees
This list will only be available for registered attendees of the event.