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Metabolism in Cancer and Stromal Cells (2nd edition)

26-27 November 2018, Leuven, Belgium
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Metabolism in Cancer and Stromal Cells (2nd edition)

Metabolism in Cancer and Stromal Cells (2nd edition)
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After a successful first edition of the VIB Conference “Metabolism in cancer and stromal cells” in September 2015, we are pleased to announce the second edition that will take place in the beautiful and historic city of Leuven.

During this international Conference we will focus on how cancer and stromal cells metabolically communicate and how their specific metabolism impacts disease development and progression. These cellular metabolism insights will offer novel therapeutic opportunities for malignant, metabolic, or inflammatory disease. In addition, also the impact of ‘omics’ technologies to study cellular metabolism will be highlighted during the meeting.

This conference will bring together internationally renowned experts who will showcase their findings on cell-type specific metabolism in cancer and beyond. By bringing together experts from different disciplines, we aim to provide a unique platform of interactions and to create a vibrant environment for discussions on novel concepts and recent technological developments.

In addition to the scientific program with plenary talks and poster sessions, there will be ample opportunities to network during the breaks, reception and conference dinner.

Submit your research:
If you are working in the field of Metabolism in Endothelial Cells, Cancer cells, Immune cells or Cancer-Associated Fibroblasts and you want to share new findings with your colleague-researchers, we would be happy to receive your abstract before 24 September! The best abstracts will be selected for oral presentation or can win the poster prize. All accepted abstracts will be included in the program book.

Poster information:
Format: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation

Meet the Expert - Prof Karen Vousden

We offer all registered junior researchers the opportunity to join our ‘Meet the Expert' session with Prof. Karen Vousden (The Francis Crick Institute, UK). During an informal round table discussion on the 26th of November (16:15 - 16:45), PhD students and postdocs will have the exclusive opportunity to ask any question/advise related to their research and careers. If you are interested in joining the free session, then send an e-mail to: conferences@vib.be.

Seating is very limited so make sure to reserve a spot soon.

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Confirmed speakers

Erika Pearce
Pearce Erika - profile picture
Erika Pearce

Erika Pearce

Johns Hopkins University & Bloomberg-Kimmel Institute for Cancer Immunotherapy, US
Susan Kaech
Kaech Susan - VIB Conferences
Susan Kaech

Susan Kaech

NOMIS Center for Immunobiology & Microbial Pathogenesis, Salk Institute for Biological Studies, US

Program

Day 1 - Monday, 26 November, 2018

08:30
09:10
Registration & Coffee
09:10
09:20
Welcome
Session 1: Metabolism of Endothelial Cells
09:20
09:55
Metabolic regulation of endothelial growth and proliferation
09:55
10:30
Endothelial Metabolism

Zolt Arany

Perelman School of Medicine, University of Pennsylvania, US
10:30
10:45
FOXO1-induced metabolite signaling enforces quiescence in the vascular endothelium

Jorge Andrade

Max Planck Institute for Heart and Lung Research, DE
Selected from abstracts
10:45
11:15
Coffee break
11:15
11:30
Endothelial FoxO1 deficiency prevents obesity-related disorders through increased endothelial glycolysis and vascular growth

Martina Rudnicki

York University, CA
Selected from abstracts
11:30
12:05
Endothelial control of muscle metabolism
12:05
12:40
Angiogenesis revisited: Role and (therapeutic) Implications of Endothelial Metabolism
12:40
13:30
Lunch
13:30
14:30
Poster session
Session 2: Metabolism of Cancer Cells
14:30
15:05
Metabolic reprogramming in human tumors in vivo

Ralph DeBerardinis

Children’s Medical Center Research Institute at UT Southwestern Medical Center, US
15:05
15:40
Metabolic limitations of cancer cell proliferation
15:40
16:15
Glutamate secretion drives exosome release to link mitochondrial metabolism with cell migration and invasion
16:15
16:30
Increased formate overflow is a hallmark of oxidative cancer and promotes invasion

Johannes Meiser

Luxembourg Institute of Health, LU
Selected from abstracts
16:30
16:35
Droplet digital PCR allows for sensitive detection and quantification of (metabolic) oncogenes.
Sponsored talk
16:35
17:05
Coffee break
17:05
17:20
Evidence for an alternative fatty acid desaturation pathway that increases metabolic plasticity in cancer cells

Kim Vriens

VIB-KU Leuven Center for Cancer Biology, BE
Selected from abstracts
17:20
17:55
Lactate and protons accumulation: consequences but also causes of cancer cell metabolic rewiring
17:55
18:30
p53 and Metabolism: Cancer and Beyond
18:30
19:15
Network reception
20:00
22:30
Conference dinner

Day 2 - Wednesday, 26 November, 2014

08:45
09:15
Coffee
Session 3: Metabolism of Immune Cells
09:15
09:50
Anti-tumor T cells- you are what you eat

Susan Kaech

NOMIS Center for Immunobiology & Microbial Pathogenesis, Salk Institute for Biological Studies, US
09:50
10:25
Acetate acts as an alternative substrate to promote T cell function during glucose restriction

Erika Pearce

Johns Hopkins University & Bloomberg-Kimmel Institute for Cancer Immunotherapy, US
10:25
10:40
A defective pentose phosphate pathway reduces inflammatory macrophage responses during hypercholesterolemia

Jan Van den Bossche

UMC Amsterdam - VUmc, NL
Selected from abstracts
01:40
11:10
Coffee break
11:10
11:45
Hierarchical control of tumor immunity by myeloid amino acid metabolism
11:45
12:20
Regulation of T cell function by one-carbon metabolism

Russell Jones

Centre for Cancer and Cell Biology, Van Andel Research Institute, US
12:20
12:25
Bring high resolution, high content imaging to life
Sponsored talk
12:25
13:10
Lunch
13:10
14:00
Poster session
Session 4: Metabolism of Cancer-Associated Fibroblasts
14:00
14:35
Cancer associated fibroblast metabolism: role of the pyruvate dehydrogenase
14:35
15:10
Identifying Metabolic Dependencies in Pancreatic Cancer
15:10
15:25
Stroma-dependent reactivation of tumor growth from mitochondrial DNA-depleted cancer cells relies on dihydroorotate dehydrogenase

Jakub Rohlena

Institute of Biotechnology, Czech Academy of Sciences, CZ
Selected from abstracts
15:25
15:55
Coffee break
Session 5: Omics Technologies
15:55
16:30
Trans-omic analysis of the liver of lean and obese mice during an oral glucose challenge
17:05
17:40
Metabolomics as a hypothesis generator for understanding metabolic regulation
17:40
17:50
Closing remarks

Organizing committee

Abstracts

The full list of abstracts will be available on 16-11-2018 until 11-12-2018
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 16-11-2018 until 11-12-2018
This list will only be available for registered attendees of the event.