Type 2 Immunity in Homeostasis and Disease

In cooperation with Cell Press
21-22 February 2019, Bruges, Belgium
Pictures of the event, added after the event has passed ...
Registration until
Thursday, 7 February, 2019
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Feb 07
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Type 2 Immunity in Homeostasis and Disease
In cooperation with Cell Press

Type 2 inflammation rich in eosinophils, basophils and mast cells and orchestrated by Th2 lymphocytes has been mainly studied in the context of allergies and immune responses to helminths. Since the discovery of type 2 innate lymphoid cells there has been a strong interest in understanding how type 2 immunity is induced and regulated, for example by barrier epithelial cells.

Given the recent introduction of new biologics that target type 2 cytokines to treat severe allergic disease, we are accumulating a lot of new insights on type 2 immune responses in humans as well.

This meeting will not only focus on new effector and regulatory mechanisms of the type 2 immune response. It will also offer a number of talks taking a broader look on type 2 immunity, dealing with such topics as type 2 immunity in homeostasis, growth and repair, metabolism, neuro-immune interactions and cancer.

Understanding these alternative roles for type 2 immunity will be important to address the benefits and potential pitfalls of long-term inhibition of type 2 immunity by biologicals and could elucidate new therapeutic pathways for very common diseases like asthma, obesity, diabetes and cancer.

Abstracts can be submitted for the following topics:

  • Tissue homeostasis and repair
  • Type 2 Neuro-immune axis
  • Type 2 in allergy, asthma & helminth infection
  • Type 2 Immunity & Cancer


Information for poster submissions:

The format for your poster should be: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation

Confirmed speakers

Ronald N. Germain

National Institutes of Health, US

David Artis

Weill Cornell Medicine, US

Andrew McKenzie

MRC Laboratory of Molecular Biology, UK

Judi Allen

The University of Manchester, UK

Elise Dalmas

INSERM, FR

Stephen J. Galli

Stanford University, US

Ana Domingos

Dept. Physiology, Anatomy, Genetics, University of Oxford, UK

Jean-Philippe Girard

CNRS - University of Toulouse, FR

Philippe Jay

INSERM, FR

Kazuyo Moro

Laboratory for Innate Immune systems, RIKEN IMS, JP

Anna Molofsky

University of California-San Francisco, US

Ariel Munitz

Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, IL

Marion Pepper

Department of Immunology, University of Washington, US

Wayne Shreffler

Massachusetts General Hospital, US

Henrique Veiga-Fernandes

Champalimaud Centre for the Unknown, PT

Steve F. Ziegler

Benaroya Research Institute, US

Bart N. Lambrecht

VIB-UGent Center for Inflammation Research, BE

Richard Locksley

Department of Medicine (Infectious Diseases), University of California San Francisco, US
Submit an abstract
Type 2 Immunity in Homeostasis and Disease

The best abstracts will be selected for a short talk in the plenary program. 

Abstract submission closing date
Saturday, 15 December, 2018
Submit abstract

Day 1 - 21 February 2019

Thursday, 21 February, 2019
08:45 - 09:15
Welcome coffee and registration
09:15 - 10:05
Opening Keynote
Benefit of mast cells and IgE during innate and acquired immune responses to venoms. Is this the "good side" of allergy?
Stephen J. Galli
Stanford University, US
Session 1: Type 2 Neuro - immune axis
10:05 - 10:40
Innate lymphocytes and the second brain
Henrique Veiga-Fernandes
Champalimaud Centre for the Unknown, PT
10:40 - 11:10
Coffee
11:10 - 11:25
Talk selected from abstracts
Presenter selected from abstracts
11:25 - 12:00
Innate immune mechanisms of developmental synapse remodeling
Anna Molofsky
University of California-San Francisco, US
12:00 - 12:35
Sympathetic neuroimmunity in Obesity
Ana Domingos
Dept. Physiology, Anatomy, Genetics, University of Oxford, UK
12:35 - 13:25
Lunch
13:25 - 14:25
Poster Session
Session 2: Tissue homeostasis and repair
14:25 - 15:00
Imaging Immunity – Using Advanced Dynamic and Multiplex Static Optical Methods to Develop a Spatiotemporal Understanding of Host Defense and Disease
Ronald N. Germain
National Institutes of Health, US
15:00 - 15:35
Macrophage Dynamics during Helminth Infection
Judi Allen
The University of Manchester, UK
15:35 - 15:50
Talk selected from abstracts
Presenter selected from abstracts
15:50 - 16:20
Coffee & Meet the Expert session
16:20 - 16:55
Type 2 immune priming of insulin secretion
Elise Dalmas
INSERM, FR
16:55 - 17:30
The function of lung resident memory Th2 cells
Marion Pepper
Department of Immunology, University of Washington, US
17:30 - 18:05
Closing talk
Richard Locksley
Department of Medicine (Infectious Diseases), University of California San Francisco, US
18:30 - 19:30
Reception at Bruges City Hall
20:00 - 22:30
Conference Dinner @ Halve Maan

Organizing Committee:
Bart Lambrecht, VIB-UGent Center for Inflammation Research, BE
Hamida Hammad, VIB-UGent Center for Inflammation Research, BE
Richard Locksley, Department of Medicine (Infectious Diseases), UCSF, US
Bruce Koppelman, Senior Scientific Editor-Immunity, Cell Press, US
Evy Vierstraete, VIB Science Events Manager, BE

Day 2 - 22 February 2019

Friday, 22 February, 2019
08:45 - 09:15
Welcome coffee and registration
Session 3: Type 2 in Allergy, Asthma & helminth infection
09:15 - 09:50
Interleukin-33 (IL-33): a tissue-derived nuclear cytokine with critical roles in allergic inflammation
Jean-Philippe Girard
CNRS - University of Toulouse, FR
09:50 - 10:25
Regulation of ILC2-mediated antigen non-specific immune responses
Kazuyo Moro
Laboratory for Innate Immune systems, RIKEN IMS, JP
10:25 - 10:40
Talk selected from abstracts
Presenter selected from abstracts
10:40 - 11:10
Coffee
11:10 - 11:45
Wayne Shreffler
Massachusetts General Hospital, US
11:45 - 12:20
Immune Regulation at barrier surfaces
David Artis
Weill Cornell Medicine, US
12:20 - 12:55
Intestinal epithelial tuft cells: sentinels of the gut mucosa
Philippe Jay
INSERM, FR
12:55 - 13:45
Lunch
13:45 - 14:45
Poster Session
Session 4: Type 2 Immunity & Cancer
14:45 - 15:20
Type 2 inflammation and cancer
Steve F. Ziegler
Benaroya Research Institute, US
15:20 - 15:35
Talk selected from abstracts
Presenter selected from abstracts
15:35 - 16:05
Coffee
16:05 - 16:40
Emerging roles for eosinophils in the tumor microenvironment
Ariel Munitz
Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, IL
16:40 - 17:15
ILC2 in the regulation of adaptive immunity and metabolism
Andrew McKenzie
MRC Laboratory of Molecular Biology, UK
17:15 - 17:50
Closing Talk
Spontaneous protein crystallization as a drugable target in type 2 immunity
Bart N. Lambrecht
VIB-UGent Center for Inflammation Research, BE

Organizing Committee:
Bart Lambrecht, VIB-UGent Center for Inflammation Research, BE
Hamida Hammad, VIB-UGent Center for Inflammation Research, BE
Richard Locksley, Department of Medicine (Infectious Diseases), UCSF, US
Bruce Koppelman, Senior Scientific Editor-Immunity, Cell Press, US
Evy Vierstraete, VIB Science Events Manager, BE

Attendees

The full list of attendees will be available on 21-02-2019 until 28-02-2019.
This list will only be available for registered attendees of the event.

Abstracts

The full list of abstracts will be available on 21-02-2019 until 28-02-2019.
Only registered attendees can download abstracts.

Venue

Old St. John Site
Zonnekemeers (parking)
8000 Brugge
Belgium

Website

Housing

If you are looking for a hotel, please use the convenient list provided by Meeting in Brugge: Check out the hotels in Bruges

Contacts
VIB Conferences