Nick works as an Independent Research Fellow in the Institute for Microbiology and Infection at the University of Birmingham, sponsored by an MRC Special Training Fellowship in Biomedical Informatics. His research explores the use of cutting-edge genomics and metagenomics approaches to the diagnosis, treatment and surveillance of infectious disease. Nick has so far used high-throughput sequencing to investigate outbreaks of important Gram-negative multi-drug resistant pathogens such as Pseudomonas aeruginosa,Acinetobacter baumannii and Shiga-toxin producing Escherichia coli. His current work focuses on the genetic diversity of Pseudomonas aeruginosa infection in chronic lung diseases such as cystic fibrosis as a diagnostic and prognostic marker. A more general aim is to develop bioinformatics tools to aid the interpretation of genome and metagenome-scale data in routine clinical practice, and to evaluate the role of novel sequencing methods and platforms.
Nick Loman's webpage