Oliver Stegle is a group leader at the EMBL European Bioinformatics Institute (EMBL-EBI) in Cambridge, UK and at the Genome Biology Unit at EMBL Heidelberg, Germany. His group develops advanced statistical approaches for analysing high-dimensional molecular traits in different contexts. By using molecular readouts, the team is deriving methods for interpreting the effect of genetic variation, including disease mutations. Most recent interests span using single-cell genomics technologies for such genetic analyses, including single-cell RNA-seq and single-cell epigenomics methods.
Read the publication: f-scLVM: Scalable and versatile factor analysis for single-cell RNA-seq