Rohit V. Pappu is the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering and Director of the Center for the Science & Engineering of Living Systems (CSELS) at Washington University in St. Louis, USA. He received his PhD in Biological Physics from Tufts University in 1996. Following his graduate work, Dr. Pappu spent five years over two postdoctoral fellowships in Molecular Biophysics at the Washington University School of Medicine in St. Louis and the Johns Hopkins University School of Medicine in Baltimore. In the fall of 2001, Dr. Pappu joined the faculty of the Department of Biomedical Engineering at Washington University in St. Louis.
Dr. Pappu’s research interests focus on the biophysical principles governing the form and functions of intrinsically disordered proteins, the physical principles underlying protein aggregation and their associations with neurodegeneration, specifically Huntington’s disease, the polymer physics of protein and RNA phase separation focusing specifically on uncovering how sequences encode the driving forces for phase transitions, and leveraging the emerging understanding of IDPs and phase separation to design soft materials with bespoke properties. These interests are driven by a novel combination of physical theories, high performance computing, and bioinformatics approaches.