Massimiliano (Max) Mazzone is a group leader of the Laboratory of Tumor Inflammation and Angiogenesis at VIB-KU Leuven Center for Cancer Biology. He is also professor at the KU Leuven Department of Oncology at the Faculty of Medicine. Karin de Visser is the group leader of the Inflammation and Cancer group at the Netherlands Cancer Institute (NKI) and Oncode Institute, and a professor at Leiden University. Join us in this double interview, where we discuss their shared passion for immuno-oncology, their research, the upcoming Immuno-Oncology conference, and much more.