Asset 2 Conferences

3rd Ghent Gut Inflammation Group Meeting

13-14 June 2019, Ghent, Belgium
Intestinal host-microbiota interactions controlling health and disease
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3rd Ghent Gut Inflammation Group Meeting

3rd Ghent Gut Inflammation Group Meeting

Intestinal host-microbiota interactions controlling health and disease

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GGIG LogoGhent University logo

The ‘Ghent Gut Inflammation Group’ represents a consortium of research labs at Ghent University studying diverse aspects of gastrointestinal biology during health and disease. Understanding how the complex interactions between the intestinal microbiota and host immune as well as stromal cells affect both intestinal and extra-intestinal health (e.g. in the brain and the joints) demands a multi-disciplinary approach. For taking on this challenge, the GGIG consortium connects expertise from 4 different UGent Faculties.

Biennially, GGIG organizes a symposium covering various aspects of intestinal biology in health and disease. The two-day symposium is specifically inviting junior scientists to present their recent work, to promote interaction and collaboration amongst young scientists, and to establish a vibrant network of young scientists studying intestinal mucosal immunology. Although the speakers are junior scientists, the symposium is open to scientists of all levels.

More information on GGIG and previous symposia on www.GGIG.be.

Information for poster submissions:

The format for your poster should be: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation

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Confirmed speakers

Ara Koh
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Ara Koh

Ara Koh

University of Gothenburg & Sahlgrenska University Hospital, SE
Konrad Aden
Aden Konrad - Profile picture
Konrad Aden

Konrad Aden

Christian-Albrechts-University Kiel & University Hospital Schleswig Holstein, Campus Kiel, DE
Paula Perez-Pardo
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Paula Perez-Pardo

Paula Perez-Pardo

Division of Pharmacology Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, NL

Program

Day 1 - Thursday, 13 June, 2019

09:00
09:30
Registration & Coffee
09:30
12:10
Session 1: Intestinal host-microbe interactions in intestinal immunity
09:30
10:00
Early priming for life - Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition

Markus Fulde

Institute of Microbiology and Epizootics, Freie Universitat Berlin, DE
10:00
10:30
Zeb2 drives invasive and microbiota-dependent colon carcinoma
10:30
11:00
IL-36R associated molecular mechanisms in colitis and intestinal fibrosis
11:00
11:30
Shaping of adaptive immunity by the intestinal microbiota
11:30
11:50
Selected abstract: Intestinal IgA shows specific broad binding to phylogenetically non-related bacteria
Selected from abstracts
11:50
12:10
Selected abstract: Edible monomeric IgA-like antibodies provide mucosal passive immunization against gastro-intestinal infection
12:10
13:00
Lunch & Poster session
13:00
15:30
Session 2: Metabolome regulation of intestinal host-microbiota interactions
13:00
13:30
Mechanistic studies of the impact of microbially produced histidine-derived metabolites on insulin signalling

Ara Koh

University of Gothenburg & Sahlgrenska University Hospital, SE
13:30
14:00
Treating Clostridioides difficile infection using microbial metabolites

Julie McDonald

Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, UK
14:00
14:30
The enterohepatic circulation: a microbial-host communication network
14:30
15:00
From Jungle to City: Effect of urbanization on microbiome and metabolome
15:00
15:30
Coffee break
15:30
16:50
Session 3: Intestinal host-microbiota interactions in infectious encounters
15:30
15:50
Selected abstract: Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection
Selected from abstracts
15:50
16:10
Selected abstract: The epithelial Naip-Nlrc4 inflammasome controls systemic spread of Salmonella Typhimurium by restricting pathogen migration from the gut lumen
16:10
16:30
Selected abstract: A20/TNFAIP3 in myeloid cells is critical for protective immunity against gastrointestinal helminths
Selected from abstracts
16:30
16:50
Selected abstract: Early intestinal infection kinetics and immune responses to Toxoplasma gondii in pigs
16:50
19:00
Networking reception

Day 2 - Friday, 14 June, 2019

08:30
09:00
Coffee
09:00
11:30
Session 4: Intestinal epithelial cell biology and organoid technologies
09:00
09:30
Investigating cell fate switches and plasticity in intestinal organoids using integrative omics approaches

Michiel Vermeulen

Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University, NL
09:30
10:00
Interleukin-22 signalling in hiPSC-derived intestinal organoids
10:00
10:30
Divide et impera - the role of the intestinal epithelium in maintaining gut homeostasis

Konrad Aden

Christian-Albrechts-University Kiel & University Hospital Schleswig Holstein, Campus Kiel, DE
10:30
10:50
Selected abstract: Beyond execution of apoptosis – Caspase-3 and 7 mediate differentiation in neonatal intestinal ex vivo cultures
10:50
11:10
Selected abstract: Drug-bug crosstalk impacts compositional and functional features of in vitro gut microbial ecosystem
11:10
11:30
Coffee break
11:30
15:20
Session 5: Impact of intestinal host-microbe interactions on the brain and in cancer
11:30
12:45
A gut feeling about the brain: understanding and preventing the cognitive impairment of preterm infants with necrotizing enterocolitis

David Hackam

Johns Hopkins University School of Medicine, Baltimore, US
Keynote speaker
12:45
14:00
Lunch & Poster session
14:00
14:30
Ileal Apoptosis and Microbiome Shape the Immunosurveillance and Prognosis of Proximal Colon Cancer

Paula Roberti

Immunology and Immunotherapy Laboratory, INSERM U1015, Institut Gustave Roussy, FR
14:30
15:00
Role of TLR4 in the gut-brain axis in Parkinson’s disease

Paula Perez-Pardo

Division of Pharmacology Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, NL
15:00
15:20
Selected abstract: Role of the inflammasome in the gut-microbiota-brain axis
15:20
15:30
Closing remarks

Organizing committee

Debby Laukens

Debby Laukens

VIB-UGent Center for Inflammation Research, intestinal barrier signaling in disease and therapy unit, Faculty of Medicine and Health Sciences, Ghent University, BE
Lars Vereecke

Lars Vereecke

VIB-UGent Center for Inflammation Research, Department of Internal Medicine and Pediatrics, Rheumatology, Ghent University, BE
Andy Wullaert

Andy Wullaert

VIB-UGent Center for Inflammation Research, Department of Internal Medicine and Pediatrics, Ghent University, BE

Abstracts

The full list of abstracts will be available on 03-06-2019 until 21-06-2019
This list will only be available for registered attendees of the event.

Attendees

The full list of attendees will be available on 03-06-2019 until 21-06-2019
This list will only be available for registered attendees of the event.