Genome Engineering and Synthetic Biology (3rd edition)

A VIB TOOLS & TECHNOLOGIES CONFERENCE
25-26 January 2018, Bruges, Belgium
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Genome Engineering and Synthetic Biology (3rd edition)
A VIB TOOLS & TECHNOLOGIES CONFERENCE

Genome Engineering and Synthetic Biology are revolutionizing Life Sciences. Driven by advances in the CRISPR-toolbox for rapid, cheap, multiplex modification of genomes and breakthroughs in DNA synthesis technologies, the pace of progress enabled by these tools in the last years has been breathtaking.

The 1st and 2nd Genome Engineering and Synthetic Biology: Tools and Technologies meeting (GESB) in September 2013 and January 2016 were a roaring success and we are pleased to announce the 3rd edition of GESB in picturesque Bruges in January, 2018. 

The conference will look at emerging tools & approaches in the field of: 

  • CRISPR and Synthetic Biology Tools
  • Gene and Genome assembly
  • Targeted Genome Engineering and Design
  • Genetic Circuits and Regulation
  • CRISPR Screens

The symposium will bring together some of the most highly regarded Academics and Companies in the world with novel technologies in several sessions. In addition to a great scientific and technology program, the conference will provide ample opportunities to network during the breaks, poster sessions, reception and the conference dinner!

Poster information:
Format: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation

Confirmed speakers

Dieter Söll

Yale University, US

Prashant Mali

University of California, US

Michael Bassik

Stanford University, Department of Genetics, US

Peter Cameron

Senior research scientist, Caribou Biosciences, US

Emily LeProust

CEO, Twist Bioscience, US

Jon Moore

CSO, Horizon Discovery, UK

Jason Steiner

Director, Business Development, Synthego, US

Benjamin P. Kleinstiver

Harvard Medical School, US

Philipp Holliger

MRC Laboratory of Molecular Biology, Cambridge, UK

Linyi Gao

Zhang Lab - Broad Institute, US

Helge Zieler

Founder/ President, Primordial Genetics, US

Tom Ellis

Imperial College London, UK

Paul Feldstein

CEO, Circularis, US

Sunghwa Choe

School of Biological Sciences, Seoul National University, KR

Tim Reddy

Duke University, US

Daniel P. Dever

Stanford University, US

Mollie Schubert

Research Scientist, Integrated DNA Technologies, US

Jason Moffat

University of Toronto, CA

Tim Brears

CEO, Evonetix, UK

Paul Diehl

COO, Cellecta Inc., US

Akihiko Kondo

Kobe University, JP

Mazhar Adli

University of Virginia, US

Alan Davidson

University of Toronto, CA

Bing C. Wang

Co-Founder & CEO, Refuge Biotechnologies, US

Elaine Shapland

Head of Build, Ginkgo Bioworks, US

Sven Panke

ETH Department of Biosystems Science and Engineering, CH

Yvonne Chen

University of California, US

Kedar Patel

Director, Zymergen, US

Steven Riedmuller

Synthetic Genomics Inc, US

Farren Isaacs

Yale University, US

Roy Bar-Ziv

The Weizmann Institute of Science, IL

Björn Högberg

Karolinska Institutet, SE

Erik Splinter

CTO & co-founder, Cergentis, NL
Download the program

Day 1 - 25 January 2018

Thursday, 25 January, 2018
08:45 - 09:15
Registration & coffee
09:15 - 09:20
Welcome
Plenary: The Genome Engineering Revolution

Chair: Silvie Van den Hoecke

09:20 - 09:55
Improving the Safety and Versatility of CRISPR Genome Editing
Benjamin P. Kleinstiver
Harvard Medical School, US
Academic speaker
09:55 - 10:20
Developing tools and technologies for precision genome editing
Peter Cameron
Senior research scientist, Caribou Biosciences, US
Company speaker
10:20 - 10:50
Coffee Break
Parallel 1: The Genome Engineering Revolution

Chair: Silvie Van den Hoecke

10:50 - 11:25
Editing, Regulating and Imaging Genome with CRISPR Technology
Mazhar Adli
University of Virginia, US
Academic speaker
11:25 - 11:50
Mitigating risk of off-target effects when using CRISPR genome editing
Mollie Schubert
Research Scientist, Integrated DNA Technologies, US
Company speaker
11:50 - 12:25
Precise editing at DNA replication forks enables multiplex genome engineering in Eukaryotes
Farren Isaacs
Yale University, US
Academic speaker
Parallel 2: Next-Generation in Synthetic Biology

Chair: Nico Callewaert

10:50 - 11:15
Balancing complexity and scale in the Foundry at Ginkgo Bioworks, Inc.
Elaine Shapland
Head of Build, Ginkgo Bioworks, US
Company speaker
11:15 - 11:50
What DNA origami can help us learn about biology
Björn Högberg
Karolinska Institutet, SE
Academic speaker
11:50 - 12:15
You Design It, We Build It
Emily LeProust
CEO, Twist Bioscience, US
Company speaker
12:15 - 12:30
Selected talk: The London DNA Foundry: Using DOE and robotics to enable automated organism engineering
David McClymont
The London DNA Foundry, GB
12:30 - 13:15
Lunch
13:15 - 14:00
Poster session
Parallel 3: Tools for CRISPR Control

Chair: Sven Eyckerman

14:00 - 14:25
Tools for target validation with CRISPR/Cas9
Jon Moore
CSO, Horizon Discovery, UK
Company speaker
14:25 - 15:00
Inhibition CRISPR-Cas9 with Bacteriophage Proteins
Academic speaker
15:00 - 15:05
New strategies & insights into CRISPR driven genome editing
Gurpreet Balrey
Global Technical Applications Manager, Merck KGaA, DE
Sponsored talk
15:05 - 15:30
Event Driven Gene Programming in Adoptive T-cell Therapy
Bing C. Wang
Co-Founder & CEO, Refuge Biotechnologies, US
Company speaker
15:30 - 16:05
Phages fight back: the functioning and prevalence of anti-CRISPRs
Alan Davidson
University of Toronto, CA
Academic speaker
Parallel 4: Engineering and Directed Evolution

Chair: Nico Callewaert

14:00 - 14:25
Promoter Tuning: Context is Crucial
Paul Feldstein
CEO, Circularis, US
Company speaker
14:25 - 15:00
Designing and Evolving Novel Chemistry
Sven Panke
ETH Department of Biosystems Science and Engineering, CH
Academic speaker
15:00 - 15:05
The Echo Acoustic Platform for Synthetic Biology. A Sound Idea!
Anna Lehto
Field Applications Scientist Europe, Labcyte, FI
Sponsored talk
15:05 - 15:30
Putting the whole genome to work: microbial and protein evolution with novel compound genes created from native protein-coding sequences
Helge Zieler
Founder/ President, Primordial Genetics, US
Company speaker
15:30 - 16:05
Engineering new functions with consideration of the host cell
Tom Ellis
Imperial College London, UK
Academic speaker
16:05 - 16:35
Coffee break
Plenary: Advanced CRISPR screens

Chair: Thomas Jacobs

16:35 - 17:10
Genome-scale genetic screens for cataloging fitness genes in human cells
Jason Moffat
University of Toronto, CA
Academic speaker
17:10 - 17:35
Optimizing Genetic Profiling and Functional Screening for Genome-Wide Analysis
Paul Diehl
COO, Cellecta Inc., US
Company speaker
17:35 - 18:10
Development of new CRISPR/Cas9-based tools to study drug interactions through knockout and directed evolution
Michael Bassik
Stanford University, Department of Genetics, US
Academic speaker
18:10 - 19:10
Reception
20:00
Conference dinner

Organizing Committee:

Nico Callewaert, PhD, Science Director, VIB-UGent Center for Medical Biotechnology
Sven Eyckerman, PhD, Expert Technologist, VIB-UGent Center for Medical Biotechnology
Massimo Santoro, PhD, Group Leader, VIB-KU Leuven Center for Cancer Biology
Thomas Jacobs, PhD, Expert Scientist, VIB-UGent Center for Plant Systems Biology
Halina Novak, PhD, VIB Manager Tech Watch
Silvie Van den Hoecke, VIB Life Sciences Technology Specialist
Evy Vierstraete, PhD, VIB Science Events Manager

Day 2 - 26 January 2018

Friday, 26 January, 2018
08:45 - 09:20
Coffee
Plenary: The Synthetic biology Revolution

Chair: Nico Callewaert

09:15 - 09:55
The Genetic Code in the Age of Synthetic Biology
Dieter Söll
Yale University, US
Academic speaker
09:55 - 10:20
Evonetix: a novel approach to DNA synthesis
Tim Brears
CEO, Evonetix, UK
Company speaker
10:20 - 10:50
Cofee break
10:50 - 11:25
Synthetic Genetics: beyond DNA and RNA
Philipp Holliger
MRC Laboratory of Molecular Biology, Cambridge, UK
Academic speaker
11:25 - 11:50
Evolution of the BioXp™ – Synthetic Biology Workflows Compressing Design Build Test
Steven Riedmuller
Synthetic Genomics Inc, US
Company speaker
11:50 - 12:25
Programmable On-Chip DNA Compartments as ‘Artificial Cells’
Roy Bar-Ziv
The Weizmann Institute of Science, IL
Academic speaker
12:25 - 13:10
Lunch
13:10 - 14:00
Poster session
Parallel 5: Targeted Genome Engineering and Design

Chair: Sven Eyckerman

14:00 - 14:35
Development of platform technologies which facilitate the construction of microbial cell factories
Akihiko Kondo
Kobe University, JP
Academic speaker
14:35 - 15:00
Enabling CRISPR applications from functional genomics to therapeutics with synthetic sgRNA
Jason Steiner
Director, Business Development, Synthego, US
Company speaker
15:00 - 15:05
Building DNA libraries for exploring combinatorial design space
Yifan Li
Senior scientist, Genscript, US
Sponsored talk
15:05 - 15:40
DNA-free genome editing with functional variants of CRISPR genome editing enzymes
Sunghwa Choe
School of Biological Sciences, Seoul National University, KR
Academic speaker
15:40 - 16:05
Applying high-throughput genome engineering to optimize a variety of microbes for industrial fermentation
Kedar Patel
Director, Zymergen, US
Company speaker
Parallel 6: Next Generation CRISPR application and design

Chair: Silvie Van den Hoecke

14:00 - 14:35
Translational CRISPR-Cas9 Genome Editing of Human Hematopoietic Stem Cells
Daniel P. Dever
Stanford University, US
Academic speaker
14:35 - 15:00
TLA Technology for targeted complete sequencing & haplotyping of (CRISPR) gene editing events; expected and unexpected findings
Erik Splinter
CTO & co-founder, Cergentis, NL
Company speaker
15:00 - 15:35
Enhancing the CRISPR-Cas genome editing toolbox though structure-guided engineering
Linyi Gao
Zhang Lab - Broad Institute, US
Academic speaker
15:35 - 15:40
CRISPR/Cas9 knockins – Get better specificity with single-stranded DNA
Cornelia Hampe
Product Manager-Scientific Support Specialist, Takara Bio Europe SAS, FR
Sponsored talk
15:40 - 15:55
Selected talk: SWITCH: Connecting CRISPR tools for genome engineering and metabolic flux control to develop Saccharomyces cerevisiae cell factories.
Katherina García Vanegas
Technical University of Denmark, DK
15:55 - 16:30
Coffee break
Plenary: Therapeutic power of genome engineering

Chair: Silvie Van den Hoecke

16:30 - 17:05
Determining Regulatory Mechanisms of Human Disease
Tim Reddy
Duke University, US
Academic speaker
17:05 - 17:40
Engineering Next-Generation T Cells for Cancer Immunotherapy
Yvonne Chen
University of California, US
Academic speaker
17:40 - 18:15
Therapeutic Strategies Via CRISPR-Cas: New Approaches and New Challenges
Prashant Mali
University of California, US
Academic speaker
18:15 - 18:25
Closing remarks

Organizing Committee:

Nico Callewaert, PhD, Science Director, VIB-UGent Center for Medical Biotechnology
Sven Eyckerman, PhD, Expert Technologist, VIB-UGent Center for Medical Biotechnology
Massimo Santoro, PhD, Group Leader, VIB-KU Leuven Center for Cancer Biology
Thomas Jacobs, PhD, Expert Scientist, VIB-UGent Center for Plant Systems Biology
Halina Novak, PhD, VIB Manager Tech Watch
Silvie Van den Hoecke, VIB Life Sciences Technology Specialist
Evy Vierstraete, PhD, VIB Science Events Manager

Attendees

The full list of attendees will be available on 01-01-1970 until 01-01-1970.
This list will only be available for registered attendees of the event.

Abstracts

The full list of abstracts will be available on 01-01-1970 until 01-01-1970.
Only registered attendees can download abstracts.